Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC6L All Species: 22.12
Human Site: Y224 Identified Species: 69.52
UniProt: Q2NKX8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2NKX8 NP_060139.2 1250 141103 Y224 G Q E F V W D Y V I L D E A H
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092609 1252 141491 Y224 G Q E F V W D Y V I L D E A H
Dog Lupus familis XP_549075 1268 143171 Y246 G Q E F V W D Y V I L D E A H
Cat Felis silvestris
Mouse Mus musculus Q8BHK9 1240 138836 Y225 G Q A F V W D Y V I L D E A H
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505482 1393 155753 Y225 G R E F V W D Y L I F D E A H
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGR3 1451 163208 Y233 H R E F K W D Y V I L D E A H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41877 1009 116656 S45 E S S D A A D S F K R F E R L
Sea Urchin Strong. purpuratus XP_781405 563 63991
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 78.8 N.A. 73.4 N.A. N.A. 49.9 N.A. N.A. 44.4 N.A. N.A. N.A. 24.7 22.9
Protein Similarity: 100 N.A. 98.4 85.8 N.A. 82.3 N.A. N.A. 63.8 N.A. N.A. 60 N.A. N.A. N.A. 42.7 33.2
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 80 N.A. N.A. 80 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 N.A. N.A. 93.3 N.A. N.A. 86.6 N.A. N.A. N.A. 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 13 13 0 0 0 0 0 0 0 75 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 88 0 0 0 0 75 0 0 0 % D
% Glu: 13 0 63 0 0 0 0 0 0 0 0 0 88 0 0 % E
% Phe: 0 0 0 75 0 0 0 0 13 0 13 13 0 0 0 % F
% Gly: 63 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 75 % H
% Ile: 0 0 0 0 0 0 0 0 0 75 0 0 0 0 0 % I
% Lys: 0 0 0 0 13 0 0 0 0 13 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 13 0 63 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 50 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 25 0 0 0 0 0 0 0 0 13 0 0 13 0 % R
% Ser: 0 13 13 0 0 0 0 13 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 63 0 0 0 63 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 75 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 75 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _